Carolina Holistic Medicine | Functional & Alternative Medicine | Charleston, SC

functional Medicine

Fascinating scientific research in the area of HPA

Fascinating scientific research in the area of HPA (hypothalamus-pituitary-adrenal) axis and the stimulating hormone of the adrenals (ACTH) for the production of Cortisol and DHEA. Turns out the precursor of ACTH is a larger molecule called pro-opiomelanocortin (POMC). Enzymatic metabolism of the larger POMC produced in the brain and other tissues is cleaved to provide ACTH a hormone that helps release cortisol from the adrenals. Low levels of cortisol especially in the morning can contribute to low-energy and fatigue.

Turns out that POMC is a precursor protein to most endorphins, those neuropeptides that have an effect on release of Dopamine (the happiness hormone) and also a part to play on other physiological structures, both neuronal and immune.

Research on Naltrexone (LDN) has shown effects on endorphins and a role to play with POMC. And many uses of this treatment for AutoImmune disease, Multiple Sclerosis (MS), Hashimotos, Pain, CFS, IBS and even cancer. For more information just ask our center. A Free 5-min consultation will determine if we are the right center for your condition to manage “Adrenal Fatigue” and autoimmune disorders with Low Dose Naltrexone (LDN) therapy. Future lectures and Webinars coming.